Ehlo All,
This is a good non-technical article from SearchExchange.com that discusses IT admins that have gone from Exchange Server 2003 to 2010 and others that are considering it. Hence bypassing Exchange 2007. I would agree with this, since the biggest change involved in moving to 2007 or 2010 is the x64 operating system. Once you have planned for x64, make the jump if you can to 2010. Jumping from 2003 to 2007 improves I/O by 70%, while going from 2003 to 2010 improves I/O by 90%. So, this will allow you to support more users on a single server than before. One of the big cost savings in upgrading.
The only word of caution is make sure your Exchange eco-system software is supported (e.g. backups, spam filtering, archiving, replication, mobile messaging [aka BlackBerry], etc). Jumping Exchange versions typically requires software upgrade especially for a x64 operating system.
-Ben
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